Wireless Neurosensor for Full-Spectrum Electrophysiology Recordings during Free Behavior

Ming Yin, David A. Borton, Jacob Komar, Naubahar Agha, Yao Lu, Hao Li, Jean Laurens, Yiran Lang, Qin Li, Christopher Bull, Lawrence Larson, David Rosler, Erwan Bezard, Grégoire Courtine, Arto V. Nurmikko
Neuron  2014  84:1170-1182
© The Author(s). 2014
Published: 04 December 2014

• Compact, lightweight, low-power, head-mounted wireless neurosensor
• High-fidelity broadband neural data in spatially unconstrained environment
• Neural population recordings from freely behaving nonhuman primates

Brain recordings in large animal models and humans typically rely on a tethered connection, which has restricted the spectrum of accessible experimental and clinical applications. To overcome this limitation, we have engineered a compact, lightweight, high data rate wireless neurosensor capable of recording the full spectrum of electrophysiological signals from the cortex of mobile subjects. The wireless communication system exploits a spatially distributed network of synchronized receivers that is scalable to hundreds of channels and vast environments. To demonstrate the versatility of our wireless neurosensor, we monitored cortical neuron populations in freely behaving nonhuman primates during natural locomotion and sleep-wake transitions in ecologically equivalent settings. The interface is electrically safe and compatible with the majority of existing neural probes, which may support previously inaccessible experimental and clinical research.

The original publication can be found here.